Aspirin twice a day keeps new COX-1 at bay

Cancer and Inflammation: An Aspirin a Day Keeps the Cancer at Bay

Live imaging of the interactions between oncogene-transformed cells and leukocytes in zebrafish reveals that PGE(2) promotes the survival and proliferation of cancer cells. Non-steroid anti-inflammatory drugs, like aspirin, are the effective inhibitors of PGE(2) production and could be used with other anti-tumor agents in the treatment of cancer.

Statin a day keeps cancer at bay. [World J Clin Oncol. 2013] - PubMed - NCBI

Abstract In addition to cholesterol reduction, statins, currently the most commonly prescribed drug in the world, have been shown to have anti-neoplastic and immunomodulatory effects. Several observational studies and meta-analyses have shown reduction in risk of multiple cancers. More recently there has been an increasing interest in the potential role of statins as adjuvant therapy after canc...

Nicotine Keeps Leaf-Loving Herbivores at Bay

Why an aspirin a day no longer keeps the doctor away ….

Aspirin, which has just celebrated its 111th anniversary, remains one of the most widely used antiplatelet agents worldwide (1). Its high efficacy has made aspirin the cornerstone of treatment in patients suffering from cardiovascular diseases; indeed, daily aspirin therapy reduces the risk of stroke, myocardial infarction and death by approximately 25% (2). Early investigation into aspirin’s p...

An amidation a day keeps apoptosis away

ot all isoforms are created equal. New results from Christiana Ruhrberg, David Shima (Cancer Research UK, London, UK), and colleagues reveal that the stickiness of vascular endothelial growth factor (VEGF) can make all the difference between blood vessels growing larger or finding new territory. VEGF initiates the formation and expansion of the vascular system. VEGF isoforms differ in their abi...